General Cell Based Assays
Eurofins Discoverx PathHunter eXpress TIM3/TIM3 Dimerization Assay, 2-Plate Kit. (93-1082E3CP5M)
The PathHunter TIM3/TIM3 Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand induced dimerization of TIM3/TIM3 receptors. This product uses EFC technology. The cell line included overexpresses TIM3 target protein fused to PK alongside TIM3 target protein fused to EA. Upon ligand-induced dimerization of TIM3/TIM3, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress BDKRB1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0639E2CP2L)
The PathHunter BDKRB1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. bradykinin) based activation of BDKRB1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged BDKRB1 and EA-tagged β-Arrestin-2. Activation of BDKRB1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam TUNEL Assay Kit - HRP-DAB
TUNEL Assay Kit - HRP-DAB
The product is subject to the following: Abcam Restricted Use Statement
Cambridge Isotope Laboratories GLYCAN-F6-13C-GAL4 (GALACTOSE-13C6, 99%), 500 PMOL
GLYCAN-F6-13C-GAL4 (GALACTOSE-13C6, 99%), 500 PMOL
ELABSCIENCE Total Cholesterol (TC) Colorimetric Assay Kit (Single Reagent, COD-PAP Method) (E-BC-K109-M) 96 Tests
Total cholesterol includes free cholesterol and cholesterol esters. Cholesterol ester can be hydrolyzed by cholesterol esterase to produce cholesterol and free fatty acid. Cholesterol is oxidized by cholesterol oxidase to produce hydrogen peroxide. In the presence of Trinder's reagent, hydrogen peroxide is catalyzed by peroxidase (POD) to produce a red quinoneimine dye, whose color intensity is directly proportional to the TC concentration and can be measured at 510 nm.
Cayman Chemical DTNB asy Reagent 1ea
An inhibitor of GAC inhibits GAC enzyme activity (EC50 10.64 nM) reduces the viability of A549 NSCLC cells (IC50 4.025 nM) reduces colony formation by and intracellular glutamate levels in A549 cells at 0.1 and 1 UM reduces tumor growth in an A549 mouse xenograft model at 100 mg/kg
Bioassay Systems Parallel Artificial Membrane Permeability Assay-BBB Kit. Assess blood brain barrier (BBB) membrane permeability of test compounds.
For quantitative determination of blood brain barrier (BBB) membrane permeability of test compounds. Key Features: Convenient. Includes all necessary equipment to run a PAMPA plate. Simple and low-cost. Procedure is easy to follow and more affordable than cell-based permeability assays. High-throughput. Can be readily automated as a high-throughput 96-well plate assay for thousands of samples per day. Method: PAMPA. Samples: Chemical compounds. Procedure: Assay takes 20 hr, hands-on time 1 hr. Kit size: 96 tests.
Abcam Lipid Assay Kit (unsaturated fatty acids)
Lipid Assay Kit (unsaturated fatty acids)
The product is subject to the following: Abcam Restricted Use Statement
Electron Microscopy Sciences Flim Sleeve 135 mm/36 exp with Frosted Open Flap
Polyguard Polypropylene film sleeves are the finest archival quality material, and are guaranteed to give you ultimate protection for your most important film negatives. Polyguard is 100% acid free, as well as being free from optical distortion. It is resistant to water, grease, oil, alkalies, and organic solvents. Polyguard is durable, yet pliable and gentle to the film and will not become brittle, crack, or abrade the film.
Type: Frosted Open Flap
Eurofins Discoverx PathHunter Flash Detection Kit, 125 (10 plates), 1,000/4,000 dp (96-well/384-well). (93-0247)
The PathHunter Flash Detection Kit is a detection kit intended for use with PathHunter cell lines or with custom cell lines made using ProLabel/PK expression vectors. This kit will provide a brighter signal with shorter kinetics than the PathHunter Detection Kit, at the cost of a shorter half life. It can be substituted in and used with any cell line that specifies use of the PathHunter Detection kit. This kit contains lysis buffer and EFC substrate to allow for detection of EFC levels in the assayed cells. This kit contains all components required to assay 10 plates (96/384-well). For detailed product information, User manual and COA, visit www.discoverx.com/products/reagents/detection-kit-93-0247.
Eurofins Discoverx PathHunter eXpress SCTR CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0237E2CP0M)
The PathHunter SCTR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. secretin) based activation of SCTR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SCTR and EA-tagged β-Arrestin-2. Activation of SCTR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress EGFR/ErbB2 Dimerization Assay, 2-Plate Kit. (93-1051E3CP14M)
The PathHunter EGFR/ErbB2 Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. EGF) induced dimerization of EGFR/ErbB2 receptors. This product uses EFC technology. The cell line included overexpresses ErbB2 target protein fused to PK alongside EGFR target protein fused to EA. Upon ligand-induced dimerization of EGFR/ErbB2, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam Lysozyme Activity Assay Kit (Fluorometric)
Lysozyme Activity Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Meso Scale Discovery U-PLEX Mouse MIP-1 ASY
The Meso Scale Discovery U-PLEX Mouse MIP-1alpha Assay Kit is a multiplex immunoassay that measures mouse macrophage inflammatory protein 1-alpha (MIP-1alpha) in serum plasma and cell culture supernatants The assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity up to 5 logs of dynamic range and low sample volume requirements This assay kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with an ECL tag calibrators and diluent The assay takes approximately 3 5 hours to run and 10 L of sample is required The kit can test up to 80 samples in duplicate
Eurofins Discoverx PathHunter eXpress GPR30 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0373E2ACP2M)
The PathHunter GPR30 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR30 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR30 and EA-tagged β-Arrestin-2. Activation of GPR30 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.